Clinical Psychology
and Psychotherapy

Clinical Psychology and Psychotherapy

Depressive Disorders: Risk Factors

Women are affected about twice as likely as men and have a younger average age of onset (cf. Marcus 2005). The reason for this is unknown.

About half of all patients report a family history of affective disorders. The positive family history appears to be correlated with an earlier age of onset, a longer duration of disease, an increased risk for the occurrence of generalized anxiety disorder, and of suicide attempts. The remission rate does not differ from those with no positive family history (cf. Hussain 2009, Nierenberg 2007, Zisook 2007).

Patients with subclinical hypothyroidism (underactive thyroid) have a significantly increased lifetime risk (50%) for developing a depressive disorder.

© Sandra Elze, M.D. & Michael Elze, M.D.
Prien am Chiemsee / Rosenheim, www.Dr-Elze.com
 

 

Further Reading...

 

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References

Depressive Disorders: Risk Factors

Husain MM, Rush AJ, Wisniewski SR, McClintock SM, Fava M, Nierenberg AA, Davis L, Balasubramani GK, Young E, Albala AA, Trivedi MH (2009). Family history of depression and therapeutic outcome: findings from STAR*D. J Clin Psychiatry 70(2): 185-95.

Marcus SM, Young EA, Kerber KB, Kornstein S, Farabaugh AH, Mitchell J, Wisniewski SR, Balasubramani GK, Trivedi MH, Rush AJ (2005). Gender differences in depression: findings from the STAR*D study. J Affect Disord 87(2-3): 141-50.
Abstract >>

Nierenberg AA, Trivedi MH, Fava M, Biggs MM, Shores-Wilson K, Wisniewski SR, Balasubramani GK, Rush AJ (2007). Family history of mood disorder and characteristics of major depressive disorder: a STAR*D (sequenced treatment alternatives to relieve depression) study. J Psychiatr Res 41(3-4): 214-21.

Zisook S, Rush AJ, Lesser I, Wisniewski SR, Trivedi M, Husain MM, Balasubramani GK, Alpert JE, Fava M (2007). Preadult onset vs. adult onset of major depressive disorder: a replication study. Acta Psychiatr Scand 115(3):196-205.

Depressive Disorders: Guidelines
 

American Psychiatric Association - APA (2010). Practice Guideline for the treatment of patients with major depressive disorder. 3rd edition. Arlington: APPI.

DGPPN, BÄK, KBV, AWMF, AkdÄ, BPtK, BApK, DAGSHG, DEGAM, DGPM, DGPs, DGRW (Hrsg) für die Leitliniengruppe Unipolare Depression (2009). S3-Leitlinie/Nationale VersorgungsLeitlinie Unipolare Depression - Kurzfassung, 1. Auflage. Berlin, Düsseldorf: DGPPN, ÄZQ, AWMF.
Online-Version >>

National Institute for Health an Clinical Excellence - NICE (Hrsg) (2009). Depression - The treatment and management of depression in adults. Clinical guideline 90. London: NICE.
Online-Version >>

National Institute for Health an Clinical Excellence - NICE (2003). Guidance on the use of electroconvulsive therapy. Technology Appraisal Guideline 59. London: NICE.
Online-Version >>

 

Depressive Störungen: Risikofaktoren  Depressive Disorders: Risk Factors  Depressive Disorders: Risk Factors

© Sandra Elze, M.D. & Michael Elze, M.D.
Prien am Chiemsee / Rosenheim, www.Dr-Elze.com
 

 




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Last updated: 03-24-2016
 

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